5 EASY FACTS ABOUT PKRRATING DESCRIBED

The activated enzyme then phosphorylates its important substrate, the translational initiation aspect eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs to the conserved spouse and children of 4 protein kinases (PKR, PERK, GCN2, HRI) that all phosphorylate eIF2α in reaction to different stimuli12, triggering the integra